He Changchun believes that knee osteoarthritis is characterized by atrophy syndrome in the root,bi syndrome in the superficiality as the basic pathogenesis.The clinical manifestations include muscle injury in early stage,muscle strain in middle stage,and bone destruction in late stage.The differentiation of symptoms from the exterior to the interior is divided into spleen and stomach weakness syndrome,muscle and meridian deficiency syndrome,and kidney essence deficiency syndrome.Based on the treatment principle of"treating muscle in the early stage,treating tendons in the middle stage,and trea...