会议论文

中文

2014

97-102

中国中西医结合学会第八届全国诊断学术会议

中国中西医结合学会第八届全国诊断学术会议论文集

2014-05-01

深圳

中国中西医结合学会诊断专业委员会

国家自然科学基金项目(81001518,81373550,81202647);霍英东教育基金会资助(131042);中国博士后科学基金(2012M521526,2013T60771);湖南省科技厅计划项目(2013RS4038)

本校为第一机构

目的探讨三磷酸腺苷(ATP)结合盒转运体A1(ATP-binding cassette transporter 1;ABC1,ABCA1)基因219单核苷酸多态性(single nucleotide polymorphism,SNP)位点与早发冠心病血瘀证发病情况的关联性。方法利用Sequenom Nanodispenser点制芯片技术及基质辅助激光解析电离时间飞行时间质谱的实验技术分别对两批实验

　　Objective:To investigate the relevance of ATP-binding cassette transporter 1 gene 219 single nucleotide polymorphism with premature coronary heart disease incidence.Methods: Using the method of Sequenom Nanodispenser chip technology and Matrix Assisted Laser Desorption Ionization Time-of-flight Mass Spectrometry to genotype on two batch of experimental group.The first batch of 4 group were divided into blood stasis syndrome group and 80patients with premature coronary heart disease、 premature coronary heart disease and 20 cases of non bloo...