Buyang Huanwu decoction improves neural recovery after spinal cord injury in rats through the mTOR signaling pathway and autophagy

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Nie, Ying;Fan, Yujie;Zhang, Xi;Li, Xiaosong;Yin, Jian;...

通讯作者：

Wang, Xiaoye;Li, Liang

作者机构：

[Nie, Ying] Hunan Univ Chinese Med, Dept Spine, Hosp 1, Changsha, Peoples R China.

[Li, Xiaosong; Zhang, Xi; Wang, Xiaoye; Fan, Yujie] Hunan Univ Chinese Med, Hunan Brain Hosp, Clin Med Sch, Dept Chinese & Western Integrat Med, Changsha 410007, Peoples R China.

[Yin, Jian; Hu, Zhaoyong; Li, Meili] Hunan Univ Chinese Med, Dept Anat, Changsha, Peoples R China.

[Li, Liang] Hunan Univ Chinese Med, Prov Key Lab TCM Diagnost, Changsha 410208, Peoples R China.

[Li, Liang] Hunan Univ Chinese Med, Key Lab TCM Heart & Lung Syndrome Differentiat &, Changsha 410208, Peoples R China.

通讯机构：

[Wang, Xiaoye; Li, Liang] H

Hunan Univ Chinese Med, Hunan Brain Hosp, Clin Med Sch, Dept Chinese & Western Integrat Med, Changsha 410007, Peoples R China.

Hunan Univ Chinese Med, Prov Key Lab TCM Diagnost, Changsha 410208, Peoples R China.

Hunan Univ Chinese Med, Key Lab TCM Heart & Lung Syndrome Differentiat &, Changsha 410208, Peoples R China.

语种：

英文

关键词：

Spinal cord injury (SCI);Buyang Huanwu decoction (BYHWD);Rubrospinal tract (RST);Red nucleus;mTOR signaling pathway;Autophagy

期刊：

JOURNAL OF SPINAL CORD MEDICINE

ISSN：

1079-0268

年：

2023

卷：

期：

页码：

99-106

DOI：

10.1080/10790268.2021.1954378

基金类别：

Major Science and Technology Projects of Hunan Province [2018SK1030]; Natural Science Foundation of Hunan ProvinceNatural Science Foundation of Hunan Province [2018JJ2289, 2019JJ50310, 2019JJ80071]; Chinese Medicine Science & Research Project of Hunan Province [202083]; First class discipline Foundation of Chinese Medicine of Hunan University of Chinese Medicine [2018ZYX01]; Research Project of Hunan Provincial Health Commission [20201863]

机构署名：

本校为第一且通讯机构

院系归属：

中医学院

第一中医临床学院

临床医学院

中医诊断研究所

摘要：

BACKGROUND: Spinal cord injury (SCI) refers to the interruption of the tracts inside the spinal cord caused by various factors. The repair of damaged axons has always been a difficult point in clinical treatment and neuroscience research. The treatment of SCI with Buyang huanwu decoction (BYHWD), a well-known recipe for invigorating Qi (a vital force forming part of any living entity in traditional Chinese culture) and promoting blood circulation, shows a good effect. METHODS: The rubrospinal tract (RST) transection model in rats was established in this study and rats were administrated with l...

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Buyang Huanwu decoction improves neural recovery after spinal cord injury in rats through the mTOR signaling pathway and autophagy

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