OBJECTIVE To explore the research situation of the evolution of the processing history, processing technology and pharmacological action of the Corni Fructus with wine. METHODS Consult and categorize the relevant research of processing historical materials of the Corni Fructus with wine and to sum up the evolution of the processing history, the records of the processing procedures, clinical efficacy and compound application of it, the variations of the chemical constituents, quality control and the pharmacological actions after being processed Corni Fructus s with wine were be summarized. RESU...