期刊论文

Wang Wei;Cai Xiong

英文

Phytomedicine

0944-7113

2019

58

152876-

10.1016/j.phymed.2019.152876

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81874369, 81703819, 81673579]; Hunan Province Universities 2011 Collaborative Innovation Center of Protection and Utilization of Hu-xiang Chinese Medicine Resources; Hunan Provincial Key Laboratory of Diagnostics in Chinese Medicine; Traditional Chinese Medicine Processing Technology Heritage Base; Key projects of Hunan Provincial Education Department [17A157]; Open Foundation Projects of Hunan Key Laboratory of Druggability and Preparation Modification for Traditional Chinese Medicine [201701]

本校为第一且通讯机构

BACKGROUND: Rheumatoid arthritis (RA) is a chronic autoimmune diseased state, characterized by hyperplasia of the synovial membrane, degradation of cartilage, and bone erosion of diarthrodial joints. Kadsura heteroclita (Roxb) Craib (Schizandraceae), a traditional Tujia ethnomedicine called Xue Tong in China, has been long used for the prevention and treatment of rheumatic and arthritic diseases, especially in the southern China. This study aimed to evaluate anti-arthritic effects of the ethanol extract of Kadsura heteroclita stems (KHS) on complete Freund's adjuvant (CFA)-induced arthritis (A...