期刊论文

Effects of moxibustion on the expression of Th1 and Th2 cytokines in gastric tumor-bearing rats

中文

免疫学杂志

1000-8861

2019

35

12

1061-1066

10.13431/j.cnki.immunol.j.20190167

国家自然科学基金(81574077) 湖南省教育厅优秀青年项目(18B257)。

本校为第一机构

目的观察艾灸对胃荷瘤大鼠瘤体内Th1、Th2类细胞因子表达的影响。方法40只体质量200~240 g SPF级SD大鼠适应性喂养1周后,采用手术胃部移植Walker-256瘤组织建立胃荷瘤模型。7 d后随机选取10只验证造模成功,剩余30只随机分入模型组、艾灸组及红外组,每组10只。自入组当日起,艾灸组第1日悬灸中脘、关元、双侧足三里,第2日悬灸双侧脾俞及胃俞;红外组第1日红外线照射胃脘部,第2日照射背部T12-T13棘突间区域;模型组第1日仰卧位固定,第2日俯卧位固定。各组每次干预20 min,每日1次,连续21 d。干预期间密切观察动物摄食量、体质量,对生存状态进行积分。干预结束后,处死动物,测量胃部瘤体体积,测算生长抑...

To observe the effect of moxibustion on the expression of Th1/Th2 cytokines in gastric tumorbearing rats, total of 40 SD rats (200~240 g) were recruited in this study. After one week’s adaptive feeding, Walker-256 tumor tissues were transplanted onto the stomach of the SD rats to establish the gastric tumor-bearing model. Seven days later, 10 rats were randomly selected to verify the success of the model. The remaining 30 rats were randomly divided into model group, moxibustion group and infrared group (10 rats per group). The rats in moxibust...