Comparative Proteomic Analysis of the Effect of the Four-Herb Chinese Medicine ANBP on Promoting Mouse Skin Wound Healing

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成果类型：

期刊论文

作者：

Chen, Li;Hou, Qian;Zhou, Zhong-Zhi;Li, Mei-Rong;Zhong, Ling-Zhi;...

通讯作者：

He, Wen-Jun;Fu, Xiao-Bing

作者机构：

[Zhong, Ling-Zhi; Cheng, Zhong-Yi; Fu, Xiao-Bing; He, Wen-Jun; Fu, XB; Chen, Li; Zhu, Zi-Ying; Li, Mei-Rong; Deng, Xiang-Dong; Hou, Qian] Chinese Peoples Liberat Army Gen Hosp, Inst Basic Med, 28 Fuxing Rd, Beijing 100853, Peoples R China.

[Chen, Li] Hunan Univ Chinese Med, Changsha, Hunan, Peoples R China.

[Zhou, Zhong-Zhi; Xiang, Cong-Lian] Hunan Univ Chinese Med, Affiliated Hosp 1, Changsha, Hunan, Peoples R China.

[Cheng, Zhong-Yi; Zhu, Jun] Jingjie PTM Biolab Hangzhou Co Ltd, Hangzhou, Zhejiang, Peoples R China.

[Fu, Xiao-Bing; He, Wen-Jun; Fu, XB] Chinese Peoples Liberat Army Gen Hosp, Affiliated Hosp 1, 51 Fucheng Rd, Beijing 100048, Peoples R China.

通讯机构：

[He, WJ; Fu, XB] C

Chinese Peoples Liberat Army Gen Hosp, Inst Basic Med, 28 Fuxing Rd, Beijing 100853, Peoples R China.

Chinese Peoples Liberat Army Gen Hosp, Affiliated Hosp 1, 51 Fucheng Rd, Beijing 100048, Peoples R China.

语种：

英文

关键词：

herbal medicine;quantitative proteomics;skin;wound healing

期刊：

INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS

ISSN：

1534-7346

年：

2017

卷：

期：

页码：

154-162

DOI：

10.1177/1534734617720623

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81421064, 81230041, 81501669, 31100705]; China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2013M542517]; Special Financial grant from the China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2015T81099]; Natural Science Foundation of Hunan ProvinceNatural Science Foundation of Hunan Province [2016JJ3100]

机构署名：

本校为其他机构

院系归属：

第一中医临床学院

摘要：

Traditional Chinese medicine has great potential to improve wound healing. ANBP, the mixture of 4 Chinese herbs—Agrimoniapilosa, Nelumbonucifera, Boswelliacarteri, and Pollen typhae—is effective in trauma treatment while its mechanism is still elusive. In this study, quantitative proteomics and bioinformatics analyses were performed to decipher the possible roles of ANBP in accelerated wound healing of mouse skin. Among all 3171 identified proteins, 90, 71, 80, and 140 proteins were found to be differently expressed in 6 hours, 3 days, 7 days...

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Comparative Proteomic Analysis of the Effect of the Four-Herb Chinese Medicine ANBP on Promoting Mouse Skin Wound Healing

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