期刊论文

Effects of Acupuncture on the Hyperplasy of Restenosis of Vascular Smooth Muscle and Gene Expression of c - foc

中文

怀化医学高等专科学校学报

2009

2

1-5

国家自然科学基金资助项目（30371809）湖南省教育厅资助项目（08（2624）

本校为第一机构

目的探讨针刺对家兔实验性动脉血管平滑肌细胞c—myc及c—foc基因表达的影响。方法家兔随机分为正常对照组（8只），再狭窄组（24只）。再狭窄组应用PTCA球囊导管对实验兔行双侧髂动脉内膜剥脱以建立动脉粥样硬化模型，术后1month髂动脉造影示50％以上狭窄者再行PTCA球囊扩张术，以建立再狭窄模型成功后，将造模动物随机分成模型组、针刺组、药物组，每组8只。自术前2d至术后14d为l疗程，针刺内关（双）、厥阴俞（双）、心俞（双）、膻中、足三里（双）等穴。标本石蜡切片，免疫组化，DAB显色，苏木素复染。观察各组血管平滑肌细胞c—myc、c—foc基因表达。结果模型组平滑肌细胞c—myc及c—foc基...

objective To observe the effects of acupuncture on the treating vascular smooth muscle cell and gene expression of c - myc, p53 in rabbits. Methods These rabbits were randomly divided into normal control （8 rabbits） and restructure （24 rabbits） groups. To establish artherosclerosis model applying FFCA saceulus proprius to denudation arteria iliaca inner membrane two sides in restructure group. One month after operation, PTCA sacculus proprius dilatation was made if arteria iliaca opacification indicates that there were artery stricture abov...