Epimedium has long been used as an ethnic drug in Asia and Europe for its high medicinal value and health benefits, which is often used for anti-tumor, anti-osteoporosis, sexual dysfunction, and other related diseases. In this research, Epimedium is reviewed in the botany, phytochemistry, pharmacology, toxicology, processing, and quality control to make it better for clinical services. More than 106 compounds, including flavonoids, polysaccharides, alkaloids, lignans, and others, were isolated from Epimedium . Based on multiple chemically active components, Epimedium has a wide range of pharma...