期刊论文

中文

中国免疫学杂志

1000-484X

2013

29

9

900-904,909

10.3969/j.issn.1000-484X.2013.09.002

国家自然科学基金资助项目（No.81072867）；

本校为第一机构

目的:通过观察艾灸对Hp胃黏膜炎性损伤大鼠胃黏膜损伤指数和胃组织匀浆液中炎性细胞因子TNF-α、IL-1β、IL-10、IL-12含量的影响,初步揭示艾灸干预Hp胃黏膜炎性损伤,保护胃黏膜损伤的机制。方法:50只健康SD大鼠随机分为5组,即空白组(A组)、Hp胃炎模型组(B组)、模型+艾灸穴位组(C组)、模型+艾灸非穴点组(D组)和模型+电针穴位组(E组)。采用Hp灌胃造模。取大鼠足三里、中脘、关元、脾俞和胃俞穴进行艾灸。参照GUTH法计算胃黏膜损伤指数(UI),采用酶联免疫法检测大鼠胃组织匀浆液中TNF-α、IL-1β、IL-12、IL-10含量。结果:艾灸可降低Hp胃黏膜炎性损伤大鼠胃黏膜损伤指数(P

Objective：To explore the effect of the content of the UI and the content of TNF-α,IL-1β,IL-12,IL-10 gastric tissue homogenate of Hp gastritis in rats with moxibustion treatment,to reveal the mechanisms of intervention Hp gastric inflammatory injury and protect the gastric mucosa in rats with moxibustion treatment.Methods：50 healthy rats were randomly assigned into 5 groups,namely control group（group A）,Hp model group（group B）,moxibustion at acupoints group（group C）,moxibustion at non-acupoints（group D） and electro-acupuncture acupoi...