After the outbreak of COVID-19,institutions of higher learning in China delayed their studies,but they suspension of classes without suspension of teaching and dearning.Online teaching has become the mainstream mode of teaching,which is undoubtedly a new challenge for the practical experimental courses.In this paper, taking Immunology experiment course of Immunology Basic and Pathogenic Biology as an example,discussing how to use the " Overpass" online experimental teaching mode, so as to achieve the experimental teaching effect of mastering experimental operation skills, cultivating scientifi...