期刊论文

Optimization of Extraction Process of Ziyin Mingmu Tablets by Orthogonal Design

中文

中国药师

1008-049X

2013

16

8

1142-1144

10.3969/j.issn.1008-049X.2013.08.017

2011年度湖南省中医药科研计划项目（编号:201124）；

本校为第一机构

目的:优选滋阴明目片的最佳提取工艺。方法:采用正交试验法,以加水量、提取时间、提取次数为考察因素,采用高效液相色谱法测定浸膏中丹酚酸B含量并以其作为考察指标,确定最佳提取条件。结果:滋阴明目片中丹酚酸B的最佳提取工艺为药材10倍水量,提取3次,每次1.5 h。结论:该方法简单可行,稳定可靠。

Objective：To optimize the extraction process of Ziyin Mingniu tablets.Method：The ultrasonic extraction process was optimized by orthogonal design with the volume of water,extraction times and extraction time as the factors.An HPLC method was used lo determine the content of salvianolic acid B in the extracts.Result：The optimal extraction process of salvianolic acid B was 1.5h extraction for 3 times with 10-fold volume of water.Conclusion：Th...