期刊论文

Study on the Water-extracting Process of Radix Ophiopogonis and Rhizoma Phragmitis in Medicated Diet Five-juice Decoction

中文

中国药师

1008-049X

2018

21

11

1912-1915+1923

10.3969/j.issn.1008-049X.2018.11.005

湖南省科技厅重点项目（编号:2016SK2034）；

本校为第一机构

目的:优选五汁饮中鲜麦冬和鲜芦根的最佳水提工艺参数,为工业化生产提供依据。方法:采用苯酚-硫酸比色法测定五汁饮提取物中多糖含量,HPLC法测定五汁饮提取液中阿魏酸含量,作为评价工艺的指标。以单因素试验考察水提工艺粉碎程度、水提方法、提取次数,正交设计试验及响应面试验设计法优化水提工艺参数。结果:最优水提工艺参数为:100℃回流法水提2次、药材粉碎成10目筛、浸泡1 h、水提时间3 h、2 h,加水量为18倍、12倍。结论:优选的五汁饮中鲜麦冬和鲜芦根水提工艺参数科学、合理、可行、成熟稳定,适合工业化生产。

Objective ： To optimize the water-extracting process parameters of Radix Ophiopogonis and Rhizoma Phragmitis in Five- juice decoction to provide the basis for industrialization. Methods： The polysaccharide content in the extraction fluid of five-juice decoction was measured by phenol-dense sulphuric acid method. The ferulic acid content in the extraction fluid of five-juice decoction was measured by HPLC. Both the polysaccharide content and ferulic acid content were taken as the indices of process evaluation. The process parameters of water-e...