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Effect of acupuncture and clomiphene in Chinese women with polycystic ovary syndrome: A randomized clinical trial

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成果类型:
期刊论文
作者:
Wu, Xiao-Ke*;Stener-Victorin, Elisabet;Kuang, Hong-Ying;Ma, Hong-Li;Gao, Jing-Shu;...
通讯作者:
Wu, Xiao-Ke
作者机构:
[Wu, Xiao-Ke; Legro, Richard S.; Ma, Hong-Li; Gao, Jing-Shu; Stener-Victorin, Elisabet; Kuang, Hong-Ying; Xie, Liang-Zhen; Hou, Li-Hui] Heilongjiang Univ Chinese Med, Affiliated Hosp 1, Dept Obstet & Gynecol, Harbin 150040, Peoples R China.
[Wu, Xiao-Ke] World Federat Chinese Med Societies, Comm Reprod Med, Beijing, Peoples R China.
[Stener-Victorin, Elisabet] Karolinska Inst, Dept Physiol & Pharmacol, Stockholm, Sweden.
[Hu, Zhen-Xing] Xuzhou Maternal & Childrens Hosp, Outpatient Dept, Xuzhou, Peoples R China.
[Shao, Xiao-Guang] Dalian Maternal & Childrens Ctr, Ctr Reprod Med, Dalian, Peoples R China.
通讯机构:
[Wu, Xiao-Ke] H
Heilongjiang Univ Chinese Med, Affiliated Hosp 1, Dept Obstet & Gynecol, Harbin 150040, Peoples R China.
语种:
英文
关键词:
polycystic ovary syndrome;clomiphene citrate;acupuncture procedure;infertility therapy
期刊:
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
ISSN:
0098-7484
年:
2017
卷:
317
期:
24
页码:
2502-2514
基金类别:
All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Legro reported serving as a consultant to Bayer, Kindex, Euroscreen, Millendo, Takeda, Clarus, Sprout, and AstraZeneca; serving as a site investigator and receiving grants from Ferring; and receiving grants from AstraZeneca. No other disclosures were reported. This work was supported by grants 201107005 and 200807002 from the National Public Welfare Projects for Chinese Medicine, JC200804 from the Heilongjiang Province Foundation for Outstanding Youths, 2011TD006 from the Intervention for PCOS Based on Traditional Chinese Medicine Theory-TianGui Disorder, and JDZX2012036 and 2015B009 from 2009 through 2016 at the First Affiliated Hospital, Heilongjiang University of Chinese Medicine from the National Clinical Trial Base in Chinese Medicine Special Projects, by the National Key Discipline of Chinese Medicine in Gynecology from 2009 through 2016, by the Heilongjiang Province "Longjiang Scholar" Program (Drs X.-K. Wu, Stener-Victorin, and Legro), and by the Chinese "Thousand Talents Plan" scholarship (Drs Legro and H. Zhang).
机构署名:
本校为其他机构
院系归属:
第一中医临床学院
摘要:
IMPORTANCE: Acupuncture is used to induce ovulation in some women with polycystic ovary syndrome, without supporting clinical evidence. OBJECTIVE: To assess whether active acupuncture, either alone or combined with clomiphene, increases the likelihood of live births among women with polycystic ovary syndrome. DESIGN, SETTING, AND PARTICIPANTS: A double-blind (clomiphene vs placebo), single-blind (active vs control acupuncture) factorial trial was conducted at 21 sites (27 hospitals) in mainland China between July 6, 2012, and November 18, 2014,...

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