A series of silane-modified rhodamine dyes for near-IR biological fluorescence imaging of Hela cells and A549 lung cancer cells: Synthesis and sensing behavior towards ions, amino acids and hypocholorous acid

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成果类型：

期刊论文

作者：

Wang, Lile;Hu, Ruicheng;Dai, Aiguo;Wu, Zhaoli;Shi, Zeya;...

通讯作者：

Ruicheng Hu

作者机构：

[Dai, Aiguo] Hunan Normal Univ, Hunan Prov Peoples Hosp, Dept Resp Med, Affiliated Hosp 1, Changsha 410016, Peoples R China.

[Wu, Zhaoli] Hunan Univ Chinese Med, Med Sch, Dept Resp Dis, Changsha 410208, Peoples R China.

[Shi, Zeya] Hunan Normal Univ, Hunan Prov Peoples Hosp, Dept Integrated TCM & Western Med, Affiliated Hosp 1, Changsha 410016, Peoples R China.

[Hu, Ruicheng] Hunan Normal Univ, Hunan Prov Peoples Hosp, Dept Sci Res, Affiliated Hosp 1, Changsha 410016, Peoples R China.

[Hu, Ruicheng] Hunan Normal Univ, Hunan Prov Peoples Hosp, Dept Resp Med, Affiliated Hosp 1, Gu Han Rd 89, Changsha 410016, Hunan, Peoples R China.

通讯机构：

[Ruicheng Hu] D

Department of Respiratory Medicine, Hunan Provincial People's Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, 410016, China

语种：

英文

关键词：

Fluorescent imaging;Rhodamine chemosensor;ClO-Imaging;Fluorescence turn on

期刊：

Dyes and Pigments

ISSN：

0143-7208

年：

2022

卷：

207

页码：

110742

DOI：

10.1016/j.dyepig.2022.110742

机构署名：

本校为其他机构

院系归属：

医学院

摘要：

HClO is recognized as an indicator for phagocytosis and inflammatory response. Excess HClO ruptures lysosomes and leads to cell apoptosis, which has been proposed as a cure for cancer treatment. As a consequence, the real-time and in situ cell imaging for HClO is highly appealed in the field of anticancer pharmacy. In this work, a series of silane-modified rhodamine fluorescers with various functional groups were designed, hoping to find a fluo-rescer with near IR emission for bio-imaging in live cells, along with unique sensing response towards ClO- over competing species. These silane-modifi...

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A series of silane-modified rhodamine dyes for near-IR biological fluorescence imaging of Hela cells and A549 lung cancer cells: Synthesis and sensing behavior towards ions, amino acids and hypocholorous acid

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