期刊论文

Effect of moxibustion on VEGF and EGF expressions in tumor tissues of rats with gastric tumor

Ya-ping Lin<&wdkj&>Jing Tan

英文

针灸推拿医学：英文版

1672-3597

2019

17

3

155-160

10.1007/s11726-019-1106-y

国家自然科学基金项目,No.81574077.

本校为第一且通讯机构

Objective: To explore the inhibitory effect of moxibustion on tumor growth and metastasis, and also its possible mechanism, in gastric tumor-bearing rats by investigating the expressions of vascular endothelial growth factor (VEGF) and epidermal growth factor (EGF). Methods: Fifty healthy Sprague-Dawley (SD) rats (half male and half female) were routinely housed for 1 week. A total of 20 rats were randomly divided into a blank group and a sham operation group, with 10 rats in each group. The remaining 30 rats were used to make gastric cancer mo...

目的:通过观察艾灸对胃荷瘤大鼠肿瘤组织中血管内皮生长因子(VEGF)和表皮细胞生子因子(EGF)表达量的影响,探讨艾灸对胃荷瘤大鼠肿瘤生长、转移的抑制情况及其可能的作用机制.方法:将50只健康Sprague-Dawley(SD)大鼠(雌雄各半)常规饲养1周后,随机选取20只分为空白组和假手术组,每组10只.剩余30只种植腹水型Walker-256癌细胞制作胃癌模型,造模成功后随机分为模型组、艾灸组和红外组,每组10只.自造模当日开始,每隔4 d称量各组大鼠体质量.艾灸组在两组穴位(中脘、关元和双侧足三里为一组,双侧脾俞和胃俞为一组)上交替施以温和灸,红外组在腹背部胃体表投影区域用短波红外线照射,两组均每日治疗1次,每...