期刊论文

Effects of needling acupoints at different nerve segments on oxytocin neurons in rat's hypothalamic paraventricular nucleus and intragastric pressure

Chun-yan Yong

英文

针灸推拿医学：英文版

1672-3597

2019

17

5

297-304

10.1007/s11726-019-1128-5

国家自然科学基金资助项目,No.81273677。

本校为其他机构

Objective: To compare and explore the effects of needling acupoints at different nerve segments on the oxytocin (OT) neurons in the paraventricular nucleus of hypothalamus (PVN) and the intragastric pressure, and discuss the possible mechanisms. Methods: Thirty-two healthy adult Sprague-Dawley (SD) rats were numbered and divided into 4 groups according to the random number table, a Zusanli (ST 36) group, a Neiguan (PC 6) group, a Weishu (BL 21) group and a control group, with 8 rats in each group. Except the control group, rats in the other three groups received acupuncture at the correspondin...

目的:比较和探讨不同神经节段腧穴对下丘脑室旁核(PVN)催产素(OT)神经元及胃内压的影响及其可能机制。方法:将32只健康成年Sprague-Dawley(SD)大鼠编号后按随机数字表法分为4组, 即足三里组、内关组、胃俞组和对照组, 每组8只。除对照组外, 其余三组大鼠分别接受相应穴位针刺。观察三个不同神经节段腧穴组大鼠针刺后PVN内OT神经元细胞和c-fos神经元细胞的双标表达及胃内压的差异。结果:与对照组比较, 足三里组和内关组的PVN内OT/c-fos的双标细胞数目减少, 胃内压升高, 组间差异均具有统计学意义(均P