期刊论文

Effect of An-pressing manipulation on post-stroke muscle spasticity in rats and its mechanism study

Jiang-shan Li

英文

针灸推拿医学：英文版

1672-3597

2020

18

2

90-95

10.1007/s11726-020-1161-4

sponsored by Fund Project of Hunan Province Education Office

本校为通讯机构

Objective: To explore the mechanism of An-pressing manipulation in improving post-stroke muscle spasticity, by observing the changes of γ-aminobutyric acid (GABA) and glycine (Gly) in plasma and gray matter of L1-L3 spinal cord anterior horn in post-stroke rats with muscle spasticity after An-pressing manipulation intervention. Methods: Ten of 80 adult male Sprague-Dawley (SD) rats were randomly selected as the blank group, and the remaining 70 were used for modeling. The middle cerebral artery occlusion (MCAO) rat model was established by ins...

目的:观察按法干预后脑卒中后肌痉挛大鼠血浆及脊髓L_1~-L_3节段灰质前角组织中γ-氨基丁酸(GABA)和甘氨酸(Gly)含量的变化,探讨按法缓解脑卒中后肌痉挛的作用机制。方法:健康成年雄性Sprague-Dawley(SD)大鼠80只,随机抽取10只为空白组,其余70只造模。采用左颈外动脉插入线栓法建立大鼠大脑中动脉局灶性脑缺血(MCAO)模型。Longa神经功能评定为2-3分,且改良Ashworth肌张力评分评定为1~-、1~+及2级的30只大鼠纳入实验。用随机数字表法将30只造模成功的大鼠随机分为模型组、按肌腱组和按肌腹组。造模成功2 d后,按肌腱组及按肌腹组大鼠分别接受大鼠按法操作治疗仪按股四头肌肌腱和按股四头肌肌腹治疗...