Serum pharmacological method has generally been used in herb study.However,preparation of test serum for ex vivo experiment is an intricate process:besides pretreatment（heat or chemicals）,it involves the proteolytic cascades of coagulation along with fibrinolysis,complement and kinin systems, as well as platelet and leukocyte activation resulting in release reactions.These processes deviate serum sample components away from the original in vivo state,and possibly also have effects on the absorbed herbal components and their downstream effecto...
