期刊论文

Progress of the Traditional Chinese Medicine in the Regulation of Ferroptosis in Cerebral Ischemia-Reperfusion Injury

中文

生理科学进展

0559-7765

2023

54

02

90-96

10.3969/j.issn.0559-7765.2023.02.002

No.81473567:国家自然科学基金 No.202008:湖南省中医药科研计划课题项目 No.2021013:湖南省中医药科研计划课题项目 No.20K097:湖南省高校创新平台开放基金项目 No.2022CX52:湖南中医药大学研究生创新课题项目

本校为第一机构

缺血性中风是一种由大脑局部血流中断引起的脑血管疾病。缺血侧脑组织的快速有效再生是治疗缺血性中风的关键措施,但在再生和复流过程中存在再灌注损伤的风险。脑缺血再灌注损伤(cerebral ischemia-reperfusi...展开更多 缺血性中风是一种由大脑局部血流中断引起的脑血管疾病。缺血侧脑组织的快速有效再生是治疗缺血性中风的关键措施,但在再生和复流过程中存在再灌注损伤的风险。脑缺血再灌注损伤(cerebral ischemia-reperfusion injury,CIRI)作用机制复杂,其过程涉及多种病理环节及信号通路。铁死亡(ferroptosis)是近年来被广泛关注的新型非凋亡性细胞死亡形式,脂质过氧化与铁超载是铁死亡的重...

Ischemic stroke is a cerebrovascular disease caused by a regional disruption of cerebral blood flow to the brain.Although rapid and effective regeneration of the ischemic brain tissue is crucial to the treatment of ischemic stroke,there exists a risk of reperfusion inju...MORE Ischemic stroke is a cerebrovascular disease caused by a regional disruption of cerebral blood flow to the brain.Although rapid and effective regeneration of the ischemic brain tissue is crucial to the treatment of ischemic stroke,there exists a risk of reperfusion injury during regeneration.The underlying mechanism of c...