期刊论文

Clinical observation of Jianghuang-yizhi capsule on the treatment of vascular dementia

中文

河北中医

1002-2619

2016

38

10

1479-1483

10.3969/j.issn.1002-2619.2016.10.008

湖南中医药大学2015年度干细胞中药调控与应用实验室开放基金资助项目（编号:2015GXB01）；

本校为第一机构

目的 观察姜黄益智胶囊治疗血管性痴呆(VD)的临床疗效和安全性.方法 将72例VD患者随机分为2组,对照组予基础药物+尼麦角林片治疗,治疗组予基础药物治疗+姜黄益智胶囊治疗,疗程3个月.观察治疗前、治疗后l、3个月进行中医证候疗效积分、简易精神状态量表(MMSE)、美国国立卫生研究院卒中量表(NIHSS)评分及安全性评价.比较2组治疗前后局部脑血流量(rCBF)变化情况.结果 治疗组中医证候总有效率83.9％,高于对照组(64.5％,P＜0.01).2组治疗1、3个月后MMSE评分均升高,NIH-SS评分均降低(P＜0.05,P＜0.01).治疗组治疗1、3个月后MMSE及NIHSS评分改善情况均优于对照组(P＜0.05,P＜0.01).2组治疗后rCBF较治疗...

Objective To observe the clinical effects and safety of Jianghuang-yizhi capsule on the treatment of vascular dementia（VD）. Methods 72 VD patients were randomly divided into two groups. The control group received primary drug and nicergoline tablets,the treatment group received primary drug and Jianghuang-yizhi capsule,continuously treatment for three months. The traditional Chinese medicine（TCM） syndrome effects,mini-mental state examination（MMSE）,national institute of health stroke scale（NIHSS） and the safety evaluation were observed ...