期刊论文

Chemical constituents from Carpesium abrotanoides

中文

中成药

1001-1528

2019

41

11

2671-2675

10.3969/j.issn.1001-1528.2019.11.023

国家自然科学基金项目(31670362) 湖南中医药大学中药学一流学科(2017)。

本校为第一机构

目的研究天名精Carpesium abrotanoides L.的化学成分。方法天名精70%乙醇提取物的乙酸乙酯部位采用硅胶、Sephadex LH-20进行分离纯化,根据理化性质及波谱数据鉴定所得化合物的结构。结果从中分离得到11个化合物,分别鉴定为( 3R,6S)-3-hydroxy-2,2,6-trimethyl-7-oxabicyclo [4.3. 0] non-9-en-8-one ( 1) 、蚱蜢酮( 2) 、 ( 3S,5R,6S)-3-hydroxy-5,6-epoxy-β-ionone ( 3) 、4-hydroxy-4-( 3-oxo-1-butenyl)-3,5,5-trimethylcyclohex-2-en-1-one ( 4) 、松脂素( 5) 、1,4-dimethoxy-2,5-diformylbenzene ( 6) 、9,10-dihydroxythymol ( 7) 、dihydro-p-cinnamic acid ( 8) 、methyl hematinat...

AIM To study the chemical constituents from Carpesium abrotanoides L.. METHODS The ethyl acetate fraction of 70% ethanol extract from C. abrotanoides was isolated and purified by silica and Sephadex LH-20,then the structures of obtained compounds were identified by physicochemical properties and spectral data. RESULTS Eleven compounds were isolated and identified as ( 3R,6S)-3-hydroxy-2,2,6-trimethyl-7-oxabicyclo [4.3. 0] non-9-en-8-one ( 1), grasshopper ketone ( 2), ( 3S,5R,6S)-3-hydroxy-5,6-epoxy-β-ionone ( 3), ( 4-hydroxy-4-( 3-oxo-1-buteny...