期刊论文

中文

中国中医药信息杂志

1005-5304

2012

19

12

4-6

10.3969/j.issn.1005-5304.2012.12.003

湖南省卫生厅中医药管理局资助项目（2009073）；

本校为第一机构

目的探讨愈痫灵方加减联合抗癫痫药(AEDs)治疗成人难治性癫痫(IE)的临床疗效与安全性。方法选择符合诊断和纳入标准的病例130例,按照Doll's临床随机表法分为治疗组和对照组,分别予愈痫灵方联合AEDs及单纯AEDs治疗。定期随诊并记录用药后患者的临床发作症状、频率及不良反应等,6个月后复查视频脑电图、肝肾功能和血常规。以总体疗效、癫痫临床症状积分及脑电图异常程度积分作为临床疗效评定指标,并对比药物保留率。结果治疗6个月后,2组总体疗效比较差异有统计学意义(P

Objective To investigate clinical effects and safety of Yuxianling Decoction and anti-epileptic drugs （AEDs） in treating adult intractable epilepsy （IE）. Methods A total of 130 available and definitely diagnosed cases were divided randomly into treatment group and control group with Doll＇s clinical table method, and was treated with Yuxianling Decoction combined with AEDs and AEDs respectively for six months. The total effective rate, scores of epilepsy and abnormal degree of video electroencephalography （VEEG） were observed as clinical ...