A NIR-II Photoactivatable \"ROS Bomb\" with High-Density Cu2O-Supported MoS2 Nanoflowers for Anticancer Therapy - 成果

首页 > 成果 > 详情

A NIR-II Photoactivatable "ROS Bomb" with High-Density Cu2O-Supported MoS2 Nanoflowers for Anticancer Therapy

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Huang, Jia;Deng, Guiming;Wang, Shuya;Zhao, Tianjiao;Chen, Qiaohui;...

通讯作者：

Huang, Q;Ai, KL

作者机构：

[Huang, Qiong; Huang, Jia; Yang, Yongqi; Zhang, Jinping] Cent South Univ, Xiangya Hosp, Dept Pharm, Changsha 410008, Peoples R China.

[Wang, Shuya; Chen, Qiaohui; Huang, Jia; Zhao, Tianjiao; Yang, Yuqi; Liu, Zhaoqian; Ai, Kelong] Cent South Univ, Xiangya Sch Pharmaceut Sci, Dept Pharmacol, Changsha 410078, Peoples R China.

[Wang, Shuya; Chen, Qiaohui; Huang, Jia; Zhao, Tianjiao; Yang, Yuqi; Liu, Zhaoqian; Ai, Kelong] Cent South Univ, Xiangya Sch Pharmaceut Sci, Hunan Prov Key Lab Cardiovasc Res, Changsha 410078, Peoples R China.

[Deng, Guiming] Hunan Univ Chinese Med, Hosp 1, Dept Infect & liver Dis, Changsha 410007, Peoples R China.

[Huang, Qiong; Yang, Yuqi; Zhang, Jinping] Cent South Univ, Xiangya Hosp, Natl Clin Res Ctr Geriatr Disorders, Changsha 410008, Peoples R China.

通讯机构：

[Huang, Q ; Ai, KL ] C

Cent South Univ, Xiangya Hosp, Dept Pharm, Changsha 410008, Peoples R China.

Cent South Univ, Xiangya Sch Pharmaceut Sci, Dept Pharmacol, Changsha 410078, Peoples R China.

Cent South Univ, Xiangya Sch Pharmaceut Sci, Hunan Prov Key Lab Cardiovasc Res, Changsha 410078, Peoples R China.

Cent South Univ, Xiangya Hosp, Natl Clin Res Ctr Geriatr Disorders, Changsha 410008, Peoples R China.

语种：

英文

关键词：

chemodynamic therapy;cuprous oxide;molybdenum disulfide;photothermal therapy;synergistic therapy

期刊：

Advanced Science

ISSN：

2198-3844

年：

2023

页码：

e2302208

DOI：

10.1002/advs.202302208

基金类别：

National Natural Science Foundation of China [21974134, 81974508]; Hunan Science Fund for Distinguished Young Scholar of China [2021JJ10067]; Innovation-Driven Project of Central South University [202045005]; Hunan Provincial Natural Science Foundation of China [2021JJ31066]; Central South University Research Programme of Advanced Interdisciplinary Studies [2023QYJC017]; Key Research Project of Ningxia Hui Autonomous Region in 2021~of China [2021BEG01001]; Key Program of Ningxia Hui Autonomous Region Natural Science Foundation of China [2022AAC02058]

机构署名：

本校为其他机构

院系归属：

第一中医临床学院

摘要：

In response to the limitations of traditional cancer synergistic photothermal–chemodynamic therapy (PTT‐CDT), MoS2–Cu2O–PEG@QE/Znpp IX (MCPQZ) can pre‐weaken tumor multiple resistance and induce severe cell apoptosis by ·OH‐induced lysosomal membrane penetration under near‐infrared light in the second region laser irradiation, thereby achieving high‐efficient synergistic therapeutic effects. Abstract The fast conversion of hydrogen peroxide (H2O2) into reactive oxygen species (ROS) at tumor sites is a promising anticancer strategy by m...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

A NIR-II Photoactivatable "ROS Bomb" with High-Density Cu2O-Supported MoS2 Nanoflowers for Anticancer Therapy

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问