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Association of high expression in rat gastric mucosal heat shock protein 70 induced by moxibustion pretreatment with protection against stress injury

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成果类型:
期刊论文
作者:
Chang, Xiao-Rong*;Peng, La;Yi, Shou-Xiang;Peng, Yan;Yan, Jie
通讯作者:
Chang, Xiao-Rong
作者机构:
Hunan Univ Tradit Chinese Med, Coll Acupuncture & Message, Changsha 410007, Hunan Prov, Peoples R China.
Yi Er Kang Healthcare Ltd Co, Changsha 410007, Hunan Prov, Peoples R China.
[Chang, Xiao-Rong] Hunan Univ Tradit Chinese Med, Coll Acupuncture & Message, 113 Shaoshan Mid Rd, Changsha 410007, Hunan Prov, Peoples R China.
通讯机构:
[Chang, Xiao-Rong] H
Hunan Univ Tradit Chinese Med, Coll Acupuncture & Message, 113 Shaoshan Mid Rd, Changsha 410007, Hunan Prov, Peoples R China.
语种:
英文
关键词:
moxibustion;Zusanli;Liangmeng;stress ulcer;gastric mucosa protection;heat shock protein 70;gastric mucosal blood flow;prostaglandin E-2;malondialdehyde;endothelin
关键词(中文):
灸术;溃疡应激;胃黏膜保护;热休克蛋白质
期刊:
世界胃肠病学杂志:英文版
ISSN:
1007-9327
年:
2007
卷:
13
期:
32
页码:
4355-4359
基金类别:
Supported by National Natural Science Foundation, No. 30572310, and Hunan Natural Science Foundation, No. 05JJ 4008
机构署名:
本校为第一且通讯机构
院系归属:
针灸推拿与康复学院
摘要:
AIM: To study the effect of moxibustion on Zusanli or Liangmeng point on gastric mucosa injury in stress-induced ulcer rats and its correlation with the expression of heat shock protein 70 (HSP70). METHODS: Sixty healthy SD rats (30 males, 30 females) were divided into control group, injury model group, Zushanli point group, Liangmeng point group. Stress gastric ulcer model was induced by binding cold stress method. Gastric mucosa ulcer injury (UI) index was calculated by Guth method. Gastric mucosa blood flow (GMBF) was recorded with a biological signal analyzer. Protein content and gene expr...
摘要(中文):
瞄准:到学习, Zusanli 或 Liangmeng 上的艾灸的效果在有热吃惊蛋白质 70 的表示(HSP70 ) 的导致压力的溃疡老鼠和它的关联在胃粘膜损害上指向。方法:六十只健康 SD 老鼠(30 男性, 30 女性) 被划分成控制组,损害模型组, Zushanli 点组, Liangmeng 点组。压力胃溃疡模型被有约束力的冷压力方法劝诱。胃粘膜溃疡损害(UI ) 索引被 Guth 方法计算。胃粘膜血流(GMBF ) 与一个生物信号分析器被记录。在胃的粘膜 HSP70 的蛋白质内容和基因表示被免疫组织化学(IHC ) 和反向的抄写聚合酶链反应(RT-PCR ) 检测。硫巴比妥方法被用来决定 malondialdehyde (MDA ) 内容。胃的粘膜 endothelin (et ) 和...

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