Efficacy of a Chinese herbal formula on hepatitis B e antigen-positive chronic hepatitis B patients

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成果类型：

期刊论文

作者：

Xing, Yu-Feng;Wei, Chun-Shan;Zhou, Tian-Ran;Huang, Dan-Ping;Zhong, Wei-Chao;...

通讯作者：

Tong, GD

作者机构：

[Zhou, Da-Qiao; Huang, Dan-Ping; Tong, Guang-Dong; Xing, Yu-Feng; Zhong, Wei-Chao; Zhou, Tian-Ran; Wei, Chun-Shan] Guangzhou Univ Chinese Med, Shenzhen Tradit Chinese Med Hosp, Dept Hepatol, Clin Med Coll 4, 1 Fuhua Rd, Shenzhen 518033, Guangdong, Peoples R China.

[Chen, Bin] Hunan Univ Chinese Med, Dept Hepatol, Hosp 1, Changsha 410007, Hunan, Peoples R China.

[Jin, Hua] Capital Med Univ, Beijing Youan Hosp, Dept Integrated Tradit & Western Med Liver Dis, Beijing 100069, Peoples R China.

[Hu, Xiao-Yu] Chengdu Univ Tradit Chinese Med, Dept Infect Dis, Affiliated Hosp, Chengdu 610032, Sichuan, Peoples R China.

[Yang, Zhi-Yun] Capital Med Univ, Beijing Ditan Hosp, Dept Integrated Tradit & Western Med Liver Dis, Beijing 100015, Peoples R China.

通讯机构：

[Tong, GD ] G

Guangzhou Univ Chinese Med, Shenzhen Tradit Chinese Med Hosp, Dept Hepatol, Clin Med Coll 4, 1 Fuhua Rd, Shenzhen 518033, Guangdong, Peoples R China.

语种：

英文

关键词：

Chronic;hepatitis;B;Chinese;Herbal;Formula;treatment;Hepatitis;B;e;antigen;clearance;Hepatitis;B;e;antigen;seroconversion;Hepatitis;B;virus;DNA;reduction;Clinical;trial

期刊：

世界胃肠病学杂志：英文版

ISSN：

1007-9327

年：

2020

卷：

期：

页码：

4501-4522

DOI：

10.3748/wjg.v26.i30.4501

基金类别：

Supported by the National Natural Science Foundation of China,No.81174263 National Science and Technology Major Project during the 12th Five-year Plan Period,No.2012ZX1005006 Sanming Project of Medicine in Shenzhen,Guangdong Province,China,No.SZSM201612074 and Science and Technology Planning Project of Guangdong Province,China,No.2017A020213016.

机构署名：

本校为其他机构

院系归属：

第一中医临床学院

摘要：

BACKGROUND No guideline recommends antiviral therapy for hepatitis B e antigen (HBeAg)positive chronic hepatitis B patients with persistently normal alanine aminotransferase levels and a high hepatitis B virus (HBV) DNA viral load. AIM To evaluate the feasibility and safety of a Chinese herbal formula as a therapeutic option for chronic HBV infection. METHODS In total, 395 patients (30–65 years old) with confirmed HBeAg-positive chronic hepatitis B infection and persistently normal alanine aminotransferase were randomized to receive either Chi...

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Efficacy of a Chinese herbal formula on hepatitis B e antigen-positive chronic hepatitis B patients

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