Objective:To observe the clinical effect of the Liuwei Wenxin granule(六味温心颗粒)on cardiac function,plasma BNP and MMP-3 in patients with chronic heart failure.Methods:124 patients were randomly divided into the control group and the treatment group,62 cases in each group.The control group was given CHF routine treatment.The treatment group was given the Liuwei Wenxin granule more.Results:The total efficiency,marked rate and cardiac function in the treatment group were significantly better than the control group(P