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Efficient Eradication of Bacterial Biofilms with Highly Specific Graphene-Based Nanocomposite Sheets

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成果类型:
期刊论文
作者:
Wang, Feiying;Tan, Jianxi;Zhang, Shengnan;Zhou, Yan;He, Dinggeng*;...
通讯作者:
He, Dinggeng;Deng, Le
作者机构:
[Zhou, Yan; Wang, Feiying; He, Dinggeng; Deng, Le; Zhang, Shengnan; Tan, Jianxi] Hunan Normal Univ, State Key Lab Dev Biol Freshwater Fish, Changsha 410081, Hunan, Peoples R China.
[Wang, Feiying] Hunan Univ Chinese Med, Med Sch, Dept Resp Dis, Changsha 410208, Hunan, Peoples R China.
[Tan, Jianxi] Changsha Customs Technol Ctr, Changsha 410004, Hunan, Peoples R China.
通讯机构:
[He, DG; Deng, L] H
Hunan Normal Univ, State Key Lab Dev Biol Freshwater Fish, Changsha 410081, Hunan, Peoples R China.
语种:
英文
关键词:
biofilm;graphene oxide;aptamer;photothermal therapy;photodynamic therapy
期刊:
ACS Biomaterials Science & Engineering
ISSN:
2373-9878
年:
2021
卷:
7
期:
11
页码:
5118-5128
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31770109, 21775036]; Changsha Municipal Natural Science Foundation [kq2014181]
机构署名:
本校为其他机构
院系归属:
医学院
摘要:
Bacterial biofilms are usually resistant to antibiotics, thus powerful methods are required for removal. Nanomaterial involving a combination of treatment modalities recently has been recognized as an effective alternative to combat biofilm. However, its targeted and controlled release in bacterial infection is still a major challenge. Here, we present an intelligent phototherapeutic nanoplatform consisting of an aptamer (Apt), indocyanine green (ICG), and carboxyl-functionalized graphene oxide (GO–COOH), namely, [email protected], for targete...

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