期刊论文

中文

现代生物医学进展

1673-6273

2011

02

283-286

10.13241/j.cnki.pmb.2011.02.052

本校为第一机构

目的：探讨急性脑梗死（ACI）患者治疗前后Hcy、ET-1、hs-CRP、TXA2水平和凝血纤溶指标的变化及临床意义。方法：分别采用ELISA法、发色底物法、凝血酶法、放射免疫法和免疫透射比浊法对68例ACI患者治疗前后Hcy、ET-1、hs-CRP、TXA2和各凝血纤溶指标水平进行检测,并以30例正常健康人作为对照组。结果：①ACI患者治疗前血浆Hcy、ET-1和血清hs-CRP、TXA2含量高于对照组（P〈0.01）,经过治疗,含量均明显下降,其中血浆Hcy、ET-1恢复至正常水平,与对照组间比较差异无统计学意义（P〉0.05）②轻、中、重型组间血浆ET-1和血清hs-CRP、TXA2含量逐渐增加,组间差异有显著性（P〈0.01或0.05）,而中重型患者...

Objective：To study the significance of Hcy,ET-1,hs-CRP,TXA2,parameters of coagulation and fibrinolysis in patients with acute cerebral infarction（ACI） before and after treatment.Methods：ELISA,chromogenic substrate assay,Clauss assay,radioimmune and immune turbidimetric method were used to determine levels of Hcy,ET-1,hs-CRP,TXA2,parameters of coagulation and fibrinolysis in 68 case with ACI before and after treatment,as well as in 30 control normal cases.Results：① Before treatment,the levels of plasma Hcy,ET-1 and serum hs-CRP,TXA2 signif...