Wnt5a is a member of the Wnts protein family,which plays an important role in the process of cell maturation,embryonic development and so on.It has been shown that the expression of Wnt5 a and its signaling pathway are closely related to angiogenesis,which play an important role in angiogenesis related diseases.In this literature review,we summarized data on wnt5 a and its signaling pathway and their involvement in angiogenesis and related diseases.Further comprehensive understanding of the function and relationship between wnt5 a and angiogenesis would enable us to develop novel diagnostic an...