Objective:To observe the efficacy of wrist-ankle acupuncture combine with auricular point pressing beans in the treat-ment of cancer pain of primary liver cancer(PHC)and its effect on psychological status and serum pain mediator.Methods:117 PHC cancer pain patients admitted to the First Affiliated Hospital of Hunan University of Traditional Chinese Medicine from March 2020 to December 2022 were selected,patients were divided into control group and combined group according to the random number table method,with 58 cases and 59 cases respectively...