期刊论文

The influence of FukeQianjin Tablets to rat＇s Caspase - 3 and Caspase - 8 expression of the fallopian tubes with chronic pelvic inflammatory disease

中文

中国民族民间医药

1007-8517

2014

23

9

8-9+11

10.3969/j.issn.1007-8517.2014.9.zgmzmjyyzz201409005

湖南省高校创新平台开放基金（10K045）；

本校为第一机构

目的:通过观察妇科千金片对SD大鼠慢性盆腔炎模型中输卵管组织Caspase-3蛋白和Caspase-8蛋白表达影响,深入探讨妇科千金片治疗慢性盆腔炎的作用机制.方法:采用大肠杆菌、金黄色葡萄球菌及解脲脲原体混合菌接种法,建立慢性盆腔炎模型,随机分成七组:空白组,模型组,假手术组,中药妇炎康(0.41g·kg-1)对照组,和妇科千金片低剂量组(0.52g· kg-1)、中剂量组(1.04g· kg-1)、高剂量组(2.08g· kg-1).经药物治疗后,解剖大鼠取输卵管组织,运用免疫细胞化学法观察Caspase-3蛋白和Caspase -8蛋白表达情况.结果:治疗21d后,与模型组比,妇科千金片低剂量组Caspase-3蛋白光密度值升高,具有明显差异(P＜0.05),妇...

Objective To study the influence of FukeQianjin Tablets to rat＇s Caspase- 3 , Caspase- 8 expression of the fallopian tubes with chronic pelvic inflammatory disease. Method The rats were established by mixed bacteria of Eseheriehia coli , Staphyloeeo- eusaureus and M. urealytieum. The rats were randomly divided into 7 groups ： the control group, the model group, the low dosage group, the middle dosage group and the high dosage group of FukeQianjin Tablets, Fuyankang group. FukeQianjin Tablets in high, middle and low dosage were used to treat c...