期刊论文

The Effect of Polysaccharide Extracted from Curculigo Orchioides Gaertn on Several Active Factors in RAW264.7 Cells

中文

中国民族民间医药

1007-8517

2017

26

7

32-34+38

10.3969/j.issn.1007-8517.2017.7.zgmzmjyyzz201707012

国家自然基金项目（81460597） 贵州省科技厅与贵阳中医学院联合基金项目（黔科合LH字[2016]7109号）.

本校为其他机构

Objective To investigate the effect of Polysaccharide extracted from Curculigo Orchioides Gaertn（COP） on several active factors in RAW264.7 cells and explore the partial mechanism of how COP activates macrophages.Methods Macrophages co-culture with COP for 36h in vitro.TNF-α and IL-1 production of the cells induced by COP were measured by ELISA.NO production in supernatant was measured by Griess reagent.Results Compared with normal control group,COP significantly increased TNF-α、IL-1和NO production （P〈0.05 or P〈0.01）in 125.00 and 62.50...