期刊论文

中文

现代中西医结合杂志

1008-8849

2013

22

23

2514-2517

10.3969/j.issn.1008-8849.2013.23.003

本校为第一机构

目的 评价葛酮通络胶囊治疗脑梗死恢复期瘀血痹阻脉络证的安全性及有效性.方 法随机、双盲双模拟、阳性平行对照、多中心研究方法进行葛酮通络胶囊的Ⅱ期临床试验.受试者共210例,A组104例给予葛酮通络胶囊500 mg+安慰剂,2次/d;B组106例给予血塞通片100 mg+安慰剂,2次/d.治疗28 d后,观察并评价其临床疗效和安全性 结果 A组和B组中风病总有效率分别为88％和77％,组间比较有显著性差异(P =0.018)A组和B组中医证候总有效率分别为84％和74％,组间比较无显著性差异(P＞0.05).治疗前2组中风病痛类量化评分比较无显著性差异(P＞0.05),治疗中与治疗后组间比较有显著性差异(P =0.045,P=0.001).2组均能改善...

Objective It is to observe the effect and safety of Getong Tongluo Capsule in treatment of cerebral infarction patients with blood stasis blockage context.Methods Phase Ⅱ clinical trial randomized,double-blind,positive parallel control,multicenter study method was executed for Getong Tongluo Capsule.The total 210 cases were divided into Group A（104 cases） and Group B（106 cases）,then were given Getong Tongluo Capsule 500mg plus placebo twice a day in Group A and was given Xuesaitong tablets 100mg plus placebo twice a day in Group B.28 days ...