期刊论文

中文

现代中西医结合杂志

1008-8849

2020

29

20

2179-2183

10.3969/j.issn.1008-8849.2020.20.003

重庆市卫生计生委中医药科技项目(ZY201802097) 湖南省大学生研究性学习和创新性实验计划项目(2017-289)。

本校为第一机构

目的 基于"乳为肝窍"理论,探讨柴胡疏肝散对高泌乳素血症大鼠乳腺组织及性激素的作用,探寻肝乳相关的现代科学依据.方法 将48只大鼠随机分为正常组8只和造模组40只,造模组大鼠采用皮下注射灭吐灵方法制成高泌乳素血症模型.将造模成功大鼠随机分为模型组、溴隐亭组、柴胡疏肝散高剂量组、柴胡疏肝散中剂量组、柴胡疏肝散高剂量组,每组8只.溴隐亭组灌胃溴隐亭水溶液2 mg/(kg·d),柴胡疏肝散低、中、高剂量组分别灌胃柴胡疏肝散药液3.15 g/(kg·d)、6.3 g/(kg·d)、12.6 g/(kg·d),正常组和模型组灌胃等容量生理盐水,均每日1次,连续30 d.末次灌胃后,腹腔注射麻醉大鼠,测量各组大鼠第3对乳头直径、高...

Objective It is to discuss the effect of Chaihu Shugan Powder(CSP)on the mammary tissues and the sex hormones of rats with hyperprolactinemia(HPRL)on the theory of“the Nipple,the Liver’s Organ”,and to seek the contemporary scientific evidences that relate to liver and breast.Methods Forty-eight rats were randomly divided into normal group(n=8)and molding group(n=40),the rats in the molding group were given paspertin by subcutaneous injection to establish HPRL models.The successful models of rats were randomly divided into model group,bromocr...