期刊论文

Effects of Zuo Gui Pills on ovarian ultrastructure and expression of autophagy-related genes in mice with premature ovarian failure

中文

现代中西医结合杂志

1008-8849

2023

32

02

147-153+235

10.3969/j.issn.1008-8849.2023.02.001

81774362:国家自然科学基金 81303004:国家自然科学基金 2018JJ2290:湖南省自然科学基金项目

本校为第一机构

目的观察左归丸对卵巢早衰小鼠卵巢超微结构及自噬相关基因表达的影响。方法取60只ICR小鼠,采用腹腔注射环磷酰胺方式建立卵巢早衰模型,将造模成功小鼠随机分为模型组、戊酸雌二醇组及左归丸低、中、高剂量组各12只,另选取12只...展开更多 目的观察左归丸对卵巢早衰小鼠卵巢超微结构及自噬相关基因表达的影响。方法取60只ICR小鼠,采用腹腔注射环磷酰胺方式建立卵巢早衰模型,将造模成功小鼠随机分为模型组、戊酸雌二醇组及左归丸低、中、高剂量组各12只,另选取12只ICR小鼠作为正常组。左归丸低、中、高剂量组分别给予13.65 g/kg、40.95 g/kg、122.85 g/kg左归丸浸膏灌胃,戊酸雌二醇组给予0.13 mg...

Objective It is to observe the effects of Zuo Gui Pills on ovarian ultrastructure and expression of autophagy-related genes in mice with premature ovarian failure.Methods Sixty ICR mice were selected and injected intraperitoneally with cyclophosphamide to establish mode...MORE Objective It is to observe the effects of Zuo Gui Pills on ovarian ultrastructure and expression of autophagy-related genes in mice with premature ovarian failure.Methods Sixty ICR mice were selected and injected intraperitoneally with cyclophosphamide to establish models of premature ovarian failure,and the successful m...