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The Effect of Herb-Partition Moxibustion on Toll-like Receptor 4 in Rabbit Aorta during Atherosclerosis

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成果类型:
期刊论文
作者:
Yue, Zeng-Hui;He, Xin-Qun;Chang, Xiao-Rong;Yuan, Jian-Ling(袁建菱);Yu, Bao-Sheng(郁保生);...
通讯作者:
Xiao-Rong Chang
作者机构:
[Yue, Zeng-Hui; He, Xin-Qun; Chang, Xiao-Rong; Liu, Mi; Fu, Ling; Zhang, Liang] College of Acu-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha, Hunan, China
[Yuan, Jian-Ling; Yu, Bao-Sheng; Shang, Li-Chao] College of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China
通讯机构:
[Xiao-Rong Chang] C
College of Acu-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha, Hunan, China
语种:
英文
关键词:
antigen;messenger RNA;toll like receptor 4;animal experiment;animal model;animal tissue;aorta;article;atherosclerosis;controlled study;female;fluorescence;gray matter;herb;immune injury;immunocompetence;immunohistochemistry;inhibition kinetics;lipid diet;male;moxibustion;nonhuman;polymerase chain reaction;priority journal;protein expression;protein function;quantitative analysis
期刊:
Journal of Acupuncture and Meridian Studies
ISSN:
2005-2901
年:
2012
卷:
5
期:
2
页码:
72-79
基金类别:
This work was supported by the National Natural Science Foundation of China (No. 30873308 , 30973802 and 81173326 ), the National Basic Research Program of China (973 Program, No. 2009CB522904 ), the Science and Technology Project of Hunan Province (No. 2011SK3095 ) and the Changsha Science and Technology Key Project (No. k1005020-31 ).
机构署名:
本校为第一且通讯机构
院系归属:
中医学院
针灸推拿与康复学院
摘要:
Objective: To explore the mechanism of Toll-like receptor (TLR4) inhibition in the delay of formation of atherosclerosis by herb-partition moxibustion. Method: Seventy-five rabbits were randomly assigned to one of five groups: blank, atherosclerosis (AS) model, direct moxibustion, herb-partition moxibustion, and drug treatment. With the exception of the blank group, all rabbits were given a high-fat diet in addition to immunologic injury to create the AS model. The experiments were carried out for 16 weeks, at which time the aorta was removed f...

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