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Toxicity evaluation of processing Evodiae fructus based on intestinal microbiota

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成果类型:
期刊论文
作者:
Liang, Xuejuan;Liu, Jing;Di, Jiaxin;Xiao, Nenqun;Peng, Yanmei;...
通讯作者:
Chen, LL
作者机构:
[Liang, Xuejuan; Peng, Yanmei; Chen, Linglong] Hunan Acad Chinese Med, Changsha, Peoples R China.
[Xiao, Nenqun; Liu, Jing; Di, Jiaxin] Hunan Univ Chinese Med, Changsha, Peoples R China.
[Tian, Qixue] Hunan Acad Tradit Chinese Med, Hunan Prov Hosp Integrated Tradit Chinese & Wester, Affiliated Hosp, Changsha, Peoples R China.
[Tian, Qixue; Chen, Linglong] Hunan Acad Tradit Chinese Med, Natl Tradit Chinese Med Proc Technol Inheritance B, Changsha, Peoples R China.
通讯机构:
[Chen, LL ] H
Hunan Acad Chinese Med, Changsha, Peoples R China.
Hunan Acad Tradit Chinese Med, Natl Tradit Chinese Med Proc Technol Inheritance B, Changsha, Peoples R China.
语种:
英文
关键词:
Evodiae fructus;hepatotoxicity;intestinal microbiota;nephrotoxic;toxicity
期刊:
Frontiers in Microbiology
ISSN:
1664-302X
年:
2024
卷:
15
页码:
1336777
基金类别:
The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This research was financially supported by Scientific research items of Hunan University of Chinese Medicine (202111) and the Natural Science Foundation of Hunan Province (No. 2023JJ60117). Hunan Province Traditional Chinese Medicine Research Project (A2024020).
机构署名:
本校为通讯机构
摘要:
BACKGROUND: With the development of healthcare services, drug efficacy, and safety have become the focus of drug use, and processing alters drug toxicity and efficacy, exploring the effects of processing on Evodiae fructus (EF) can guide the clinical use of drugs. METHODS: Fifty male Kunming mice were randomly divided into the control group (CCN), raw small-flowered EF group (CRSEF), raw medium-flowered EF group (CRMEF), processing small-flowered EF group (CPSEF), and processing medium-flowered EF group (CPMEF). The CRSEF, CRMEF, CPSEF, and CPM...

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