Objective To structure one equation model on the relationship of the psychological stress re-sponse and its influential factors of inpatients. Methods This cross-sectional designed study used a stratified-ran-dom-clnster method to recruit 754 inpatients, who were asked to fill out a series of questionnaires assessing hospital stressor, social support, personality, coping style, serf-efficacy, and stressful mental response. Statistic description,analysis of variance (ANOVA), correlations, multiple linear regressions, confirmatory factor analysis...