期刊论文

A Case of Nail Transverse Groove and Elevated Uric Acid in Lung Adenocarcinoma Treated with Dacomitinib

中文

临床医学进展

2161-8712

2023

5

7461-7465

本校为第一机构

目的:报道1例达可替尼治疗肺腺癌后出现甲横沟和尿酸升高。方法:描述1名90岁的肺腺癌晚期患者经基因检测提示EGFR 21号外显子突变,予以达可替尼靶向治疗后出现副反应。结果:达可替尼靶向治疗1月后出现口腔溃疡、腹泻、手指...展开更多 目的:报道1例达可替尼治疗肺腺癌后出现甲横沟和尿酸升高。方法:描述1名90岁的肺腺癌晚期患者经基因检测提示EGFR 21号外显子突变,予以达可替尼靶向治疗后出现副反应。结果:达可替尼靶向治疗1月后出现口腔溃疡、腹泻、手指和脚趾开裂并疼痛,复查实验室检查异常的有血红蛋白、淋巴细胞绝对值、白蛋白、钙、癌胚抗原较基线资料下降,尿酸较前升高。双手手指出现甲横...

Objective: To report for the first time a case of elevated nail transverse groove and uric acid after dacomitinib treatment for lung adenocarcinoma. Methods: A 90-year-old patient with advanced lung adenocarcinoma with genetic testing suggesting EGFR21 exon mutation dev...MORE Objective: To report for the first time a case of elevated nail transverse groove and uric acid after dacomitinib treatment for lung adenocarcinoma. Methods: A 90-year-old patient with advanced lung adenocarcinoma with genetic testing suggesting EGFR21 exon mutation developed side effects after targeted treatment with da...