Bacterial characteristics in intestinal contents of antibiotic-associated diarrhea mice treated with qiweibaizhu powder

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成果类型：

期刊论文

作者：

Hui, Huaying;Wu, Yi;Zheng, Tao;Zhou, Sainan*;Tan, Zhoujin

通讯作者：

Zhou, Sainan;Tan, ZJ

作者机构：

[Zhou, Sainan; Tan, Zhoujin; Hui, Huaying; Wu, Yi; Zheng, Tao] Hunan Univ Chinese Med, Changsha, Hunan, Peoples R China.

通讯机构：

[Zhou, SN; Tan, ZJ ] H

Hunan Univ Chinese Med, Changsha, Hunan, Peoples R China.

语种：

英文

关键词：

9 metagenome DNA;antibiotic agent;cefradine;Chinese drug;distilled water;gentamicin;qiweibaizhu powder;RNA 16S;unclassified drug;antiinfective agent;RNA 16S;Acidobacteria;Actinobacteria;adult;animal experiment;animal model;antibiotic associated diarrhea;Article;bacterial gene;bacterial growth;bacterial infection;bacterium identification;biodiversity;bioinformatics;cell differentiation;Chinese medicine;community structure;comparative study;controlled study;Coriobacteriaceae;cyanobacterium;depression;disease association;DNA extraction;erected hair;female;food intake;gene sequence;intestine flora;male;microbial community;microbial diversity;mouse;nonhuman;phylogenetic tree;polymerase chain reaction;population abundance;Proteobacteria;RNA sequencing;taxonomy;Verner Morrison syndrome;animal;bacterium;China;Chinese medicine;diarrhea;drug effect;genetics;intestine;microbiology;pharmacology;powder;procedures;stomach juice;Animals;Anti-Bacterial Agents;Bacteria;China;Diarrhea;Female;Gastrointestinal Contents;Gastrointestinal Microbiome;Intestines;Male;Medicine, Chinese Traditional;Mice;Powders;RNA, Ribosomal, 16S

期刊：

MEDICAL SCIENCE MONITOR

ISSN：

1643-3750

年：

2020

卷：

页码：

e921771

DOI：

10.12659/MSM.921771

基金类别：

Sainan Zhou, e-mail: hnzhousainan@163.com, Zhoujin Tan, e-mail: tanzhjin@sohu.com This work was supported by grants from the National Natural Science Foundation of China (No: 81573951), grants from the Discipline Construction Project of Chemical Engineering and Technology of Hunan University of Chinese Medicine

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摘要：

Background: Qiweibaizhu powder (QWBZP) is a classical prescription of traditional Chinese medicine (TCM) to treat diarrhea in pediatric patients. Its use in health care practices and interventions has shown its effect on antibiotic-associated diarrhea (AAD). It is known that the occurrence of AAD is related to an imbalance of intestinal micro-ecology. Previous studies found that QWBZP could regulate the amount of some cultured microbes and the activities of lactase and sucrase in AAD mice. In order to investigate the treatment mechanism of QWBZ...

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Bacterial characteristics in intestinal contents of antibiotic-associated diarrhea mice treated with qiweibaizhu powder

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