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Soybean isoflavones modulate gut microbiota to benefit the health weight and metabolism

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成果类型:
期刊论文
作者:
Huang, Lili;Zheng, Tao;Hui, Huaying;Xie, Guozhen
作者机构:
[Huang, Lili] Hunan Univ Chinese Med, Coll Chinese Med, Changsha, Peoples R China.
[Hui, Huaying; Xie, Guozhen; Zheng, Tao] Hunan Univ Chinese Med, Sch Pharm, Changsha, Peoples R China.
语种:
英文
关键词:
Soybean isoflavones;Gut Microbiota;enzyme activity;Metabolism;short-chain fatty acids
期刊:
Frontiers in Cellular and Infection Microbiology
ISSN:
2235-2988
年:
2022
卷:
12
页码:
1004765
基金类别:
This work was supported by the National Natural Science Foundation of China (81804076), the Natural Science Foundation of Hunan Province (2020JJ5426).
机构署名:
本校为第一机构
院系归属:
药学院
摘要:
Soybean isoflavones (SIs) are widely found in food and herbal medicines. Although the pharmacological activities of SIs have been widely reported, their effects on the intestinal microecology of normal hosts have received little attention. Five-week-old Kunming (KM) mice were administered SIs (10 mg/kg/day) for 15 days. Food intake, body weight, and digestive enzyme activity were measured. Small intestine microbiota, including lumen-associated bacteria (LAB) and mucosa-associated bacteria (MAB), were analyzed using 16S ribosomal ribonucleic acid (16S rRNA) gene sequencing. Short-chain fatty ac...

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