Quercetin regulates fibrogenic responses of endometrial stromal cell by upregulating miR-145 and inhibiting the TGF-β1/Smad2/Smad3 pathway

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Xu, Jia;Tan, Ya-Li;Liu, Qi-Ying;Huang, Zi-Chun;Qiao, Zong-Hui;...

通讯作者：

Lei, Lei

作者机构：

[Qiao, Zong-Hui; Xu, Jia] Hunan Univ Tradit Chinese Med, Dept Gynaecol & Obstet, Affiliated Hosp 1, Changsha 410007, Peoples R China.

[Tan, Ya-Li; Lei, Lei] Hunan Univ Chinese Med, Coll Integrated Tradit Chinese & Western Med, Changsha 410208, Peoples R China.

[Liu, Qi-Ying] Changsha Maternal & Child Hlth Hosp, Dept Gynaecol & Obstet, Changsha 410000, Peoples R China.

[Huang, Zi-Chun] Hunan Univ Tradit Chinese Med, Affiliated Hosp 2, Dept Gynaecol, Changsha 410005, Peoples R China.

[Hu, Zhi-Qiang; Li, Tai] Hunan Univ Chinese Med, Sch Clin Med, Changsha 410208, Peoples R China.

通讯机构：

[Lei, Lei] H

Hunan Univ Chinese Med, Coll Integrated Tradit Chinese & Western Med, Changsha 410208, Peoples R China.

语种：

英文

关键词：

Endometrial fibrosis;microRNA-145;quercetin;TGF-β1;TGFBR2

期刊：

Acta Histochemica

ISSN：

0065-1281

年：

2020

卷：

122

期：

页码：

151600

DOI：

10.1016/j.acthis.2020.151600

基金类别：

This work was supported by First class discipline open fund for integration of traditional Chinese and Western Medicine of Hunan University of traditional Chinese Medicine (No. 2018ZXYJH09 ).

机构署名：

本校为第一机构

院系归属：

第一中医临床学院

第二中医临床医学院

中西医结合学院

临床医学院

摘要：

Objectives: Aim of this study is to explore whether quercetin can inhibit the enlarged fibrogenic responses of endometrial stromal cells by increasing the level of microRNA-145 (miR-145) and mediating the TGFβ1/Smad2/Smad3 signaling pathway, and to discuss the mechanism of signal transduction, further to provide experimental basis for revealing the pathophysiological mechanism and seeking new strategies for effective prevention and treatment of endometrial fibrosis. Methods: The expression levels of miR-145 and TGF-β receptor 2 (TGFBR2) were ...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Quercetin regulates fibrogenic responses of endometrial stromal cell by upregulating miR-145 and inhibiting the TGF-β1/Smad2/Smad3 pathway

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问