期刊论文

Zhou, Q.

中文

中华男科学杂志

1009-3591

2012

18

5

460-465

10.13263/j.cnki.nja.2012.05.003

国家自然科学基金（81173264） 湖南省自然科学基金（10JJ3004）

本校为第一机构

目的:观察麝香、乳香配伍组合对虎杖提取物治疗慢性非细菌性前列腺炎模型大鼠前列腺组织病理及炎症因子表达的影响。方法:53只健康雄性Wistar大鼠,5只用于大鼠前列腺蛋白提纯液的制备,48只随机分为麝香配伍乳香+虎杖提取物组、虎杖提取物、模型组、正常对照组共4组。除正常对照组外,应用大鼠前列腺蛋白提纯液辅以免疫佐剂制备实验性慢性非细菌性前列腺炎大鼠模型,造模60 d时正常对照组、模型组予生理盐水,虎杖提取物、麝香配伍乳香+虎杖提取物组分别予生药量虎杖1.575 g/（kg.d）、麝香0.021 g/（kg.d）、乳香1.05 g/（kg.d）按组别选用连续灌胃,各组给药14 d时处死,检测指标包括病理学,ELISA法...

OBJECTIVE: To observe the effects of musk and carterii birdw on the pathology and the expressions of inflammatory cytokines in chronic non-bacterial prostatitis (CNBP) rats treated with polygonum extract. METHODS: Five male Wistar rats were used for the preparation of SC purified prostate protein solution, and another 48 randomly divided into four groups: polygonum extract, polygonum extract + musk and carterii birdw, CNBP model control and normal control. CNBP models were established by injecting SC purified prostate protein solution and Freund's complete adjuvant. At 60 days after modeling, ...