Objective: to study the effects of different extracts Xiongma decoctionon plasma of 5-HT and 5-HIAA on animal model of migraine with reserpine.Method: 120 mouse were randomly divided into 11 groups: blank group(A), model group(B), volatile oil group(C), Petroleum ether extract group(D), Ethyl acetate extract group(E), n-butyl alcohol extract group(F), Ethyl acetate extract plus n-butyl alcohol extract group(G),Surplus liquid water after extract group(H),Water alcohol sink group(Ⅰ), Xiongma decoction extract group(J),Ibuprofen group(K).Thro...