(81303123):国家自然科学基金项目
(15K090):湖南省教育厅创新平台项目
(201510541002):国家级大学生创新创业训练计划项目
(2015-202,219,2016-281):湖南省大学生研究性学习与创新性实验计划项
(81303123):National Natural Science Foundation of China
(15K090):Hunan Provincial Department of Education Innovation Platform Project
(201510541002):National Undergraduate Training Programs for Innovation and Entrepreneurship
(2015-202,219,2016-281):Research-based Learning and Innovative Experimental Project of College Students of Hunan Province
The incidence of ovarian reproductive diseases such as premature ovarian failure and polycystic ovary syndrome are increasing, which has become the diseases that harm to female physical and psychological health seriously. Current studies suggest that follicular atresia in ovarian reproductive diseases has a great relationship with apoptosis of oocyte and granulosa cell. However, with the deepening of the study, researchers find that apoptosis is not the only factor that cause follicular atresia. Induced autophagy can also act on human granulosa cell and oocyte so as to participate in the folli...