期刊论文

中文

中华生殖与避孕杂志

2096-2916

2018

38

5

406-409

10.3760/cma.j.issn.2096-2916.2018.05.011

(81403427):国家自然科学基金 (2014117):湖南省中医药管理局中医药科研计划课题资助项目 (81403427):National Natural Science Foundation of China (2014117):Hunan Provincial Administration of Traditional Chinese Medicine

本校为第一机构

目的观察定坤丹对卵巢储备功能下降（DOR）导致月经后期肾虚证的临床疗效。方法 62例患者,按随机数字表法随机分为治疗组和对照组,每组31例,治疗组用中成药定坤丹,对照组用西药克龄蒙,均治疗3个月,比较患者治疗前后的中医临床证候积分、卵泡刺激素（FSH）、FSH/黄体生成激素（LH）、抗苗勒管激素（AMH）、平均卵巢体积（MOV）、窦卵泡计数（AFC）等改善情况。结果治疗组总有效率为93.55%,对照组为83.87%,治疗后组间中医临床证候的疗效分布差异有统计学意义（P=0.006 8）。激素水平和MOV改善方面,治疗组与对照组的疗效基本相当,但定坤丹在改善AMH及AFC方面优于克龄蒙。结论定坤丹对肾虚型月经后期...

Objective To evaluate curative effect of Ding Kudan (DKD) on kidney-deficency syndrome of delayed menorrhea due to decreasing ovarian reservation (DOR). Methods Sixty-two patients were divided into treatment group and control group randomly, 31 patiens for each group, the treatment group applied DKD and the latter applied climen for three months.The clinical syndrome scores, follicle-stimulating hormone (FSH), FSH/luteinizing hormone (LH), anti-Mullerian hormone (AMH), mean ovary volume (MOV) and antral follicle count (AFC) scores of the patients before and after treatment were compared. Resul...