期刊论文

中文

中药药理与临床

1001-859X

2011

27

5

74-76

10.13412/j.cnki.zyyl.2011.05.026

国家科技部973资助项目：中药药性理论相关基础问题研究（2007CB512603） 湖南省中药重点学科

本校为第一机构

目的：通过檀香对寒凝气滞的胃实寒大鼠胃排空、cAMP、cGMP及cAMP/cGMP的影响的影响,探讨檀香的行气作用。方法：采用冰水浸泡加冰水给大鼠灌胃造成寒凝气滞的胃实寒模型,观察檀香不同提取部位对大鼠胃排空、cAMP、cGMP及cAMP/cGMP的影响的影响。结果：檀香水煎液0.91g/kg对胃肠道功能有抑制作用,檀香乙醚萃取物0.91g/kg对胃肠功能有促进作用。檀香挥发油0.91g/kg能升高cAMP和cAMP/cGMP值,檀香挥发油对物质代谢有促进作用。结论：檀香行气作用的物质基础是水煎液及低极性的物质,檀香对物质代谢的调节作用主要通过挥发油来起作用。

Objective ：Through the sandalwood with stomach real cold rat gastric emptying,cAMP,cGMP and cAMP/cGMP influence.Explore the sandalwood dredging the role of material base.Methods：Using water soak with iced water method of rats caused stomach real cold rat model.Observe the sandalwood of the different extracted parts of rat gastric emptying,cAMP,cGMP and cAMP/cGMP influence.Results：Model the results of experiments showed that the sandalwood water decoction of 0.91 g/kg of gastrointestinal function have inhibition,sandalwood ether extract 0.91 ...