期刊论文

Study Progress on Compounds,Pharmacological Action and Clinical Application of Siwu Decoction

中文

中药药理与临床

1001-859X

2020

36

06

221-229

10.13412/j.cnki.zyyl.20201110.002

长沙市科技计划项目（编号:kq1901067）； 湖南省自然科学基金青年基金（编号:2020JJ5328）； 湖南中医药大学中药学一流学科项目[编号:校行科字（2018）3号]；

本校为第一机构

四物汤是唐朝蔺道人《仙授理伤续断秘方》中记载的经典方药,由当归、熟地黄、川芎和白芍四味中药组成,应用广泛,具有较高的临床价值。有补血活血之功,临床主要用于血虚及放化疗后血虚、再生障碍性贫血、血瘀证、骨折及术后失血、月经不调、功能性子宫出血、原发性痛经、绝经后骨质疏松等疾病,且对上述症状具有较好的临床疗效。其临床功效主要通过参与调节骨髓造血、血液流变、发挥雌激素样作用等实现,含有并鉴定了100余种成分,是其发挥药效活性的重要物质基础。四物汤代谢组学、蛋白质组学和网络药理学等系统生物学的研究为阐明其潜在作用机制,扩大临床应用提供了科学依据。本文通过对四物汤的物...

Siwu Decoction is a classical prescription in Lin Taoist's Xianshoulishangxuduanmifang,which is composed of four traditional Chinese medicines: Angelica sinensis (Oliv.) Diels,Ligusticum chuanxiong Hort.,Cynanchum otophyllum Schneid. and Rehmanniae radix preparata. It has been widely applied in clinic and has a good value. It mainly has Huoxue and Buxue effects,which have the obvious clinical effect on Xuexu syndrome,Xuexu syndrome after radiotherapy and chemotherapy,aplastic anemia,Xuyu syndrome,the facture,the postoperative bleeding,the irregular menstruation,the functional uterine bleeding,...