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Identification and Comparison of Potential Biomarkers by Proteomic Analysis in Traditional Chinese Medicine-Based Heart Failure Syndromes

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成果类型:
期刊论文
作者:
Jiang, Yang;Zhao, Qi;Huang, Shumin;Cheng, Bin;Hu, Zhixi
通讯作者:
Hu, ZX
作者机构:
[Zhao, Qi; Jiang, Yang] Hunan Acad Tradit Chinese Med, Affiliated Hosp, Changsha 410006, Peoples R China.
[Hu, Zhixi; Cheng, Bin; Hu, ZX; Huang, Shumin; Jiang, Yang] Hunan Univ Chinese Med, Coll Tradit Chinese Med, Changsha 410208, Peoples R China.
通讯机构:
[Hu, ZX ] H
Hunan Univ Chinese Med, Coll Tradit Chinese Med, Changsha 410208, Peoples R China.
语种:
英文
期刊:
Evidence-Based Complementary and Alternative Medicine
ISSN:
1741-427X
年:
2022
卷:
2022
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81774208]; General Projects of Hunan Natural Science Foundation [2020JJ4062]; Research and Innovation Projects of Graduate Students in Hunan Province [CX20190561]
机构署名:
本校为第一机构
院系归属:
中医学院
摘要:
Heart failure (HF) is an epidemic disease affecting a large population worldwide. Traditional Chinese medicine (TCM) is playing an increasingly important role in the clinical treatment of HF. According to the TCM theory, HF could be classified into Yang deficiency and Qi-yin deficiency; however, there are few objective and biological lines of evidence for differentiation of TCM HF syndromes to date. In this study, data-independent acquisition (DIA) mass spectrometry was applied to comparatively analyze the protein expression in serum samples ob...

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